Research NewsBiochemistry

Hijacking a Cell's Chemical Paths to Make New Antibiotics

Science  18 Jul 1997:
Vol. 277, Issue 5324, pp. 319
DOI: 10.1126/science.277.5324.319

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Many antibiotics have a complex molecular architecture that makes them extremely difficult to synthesize, making it hard to create new ones to combat resistant bacteria. On page 367, however, a group of biochemists describes a way to hijack the antibiotic-producing chemical pathways of bacteria, exploiting them to produce a wide variety of new compounds.