Research NewsGenome Sequencing

Laboratory Workhorse Decoded

See allHide authors and affiliations

Science  05 Sep 1997:
Vol. 277, Issue 5331, pp. 1432-1434
DOI: 10.1126/science.277.5331.1432

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


On page 1453 of this issue, researchers report the complete sequence of all 4.6 million base pairs in the genome of the bacterium Escherichia coli. The achievement not only marks the end of a 15-year race to determine the sequence, but because E. coli has been so well studied over the years, researchers can now use the sequence to provide a coherent picture of the organism's complete biology. It will also help in identifying the genes of higher organisms, and together with the sequences of several other bacteria, it will increase our understanding of bacterial evolution.