Research NewsBiomedicine

Blunting Nature's Swiss Army Knife

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Science  12 Sep 1997:
Vol. 277, Issue 5332, pp. 1602-1603
DOI: 10.1126/science.277.5332.1602

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Proteases, enzymes that cut proteins into pieces, have been implicated in everything from the replication of viruses to the tissue damage of arthritis and asthma to cancer metastasis and parasite reproduction. Now, researchers are developing a raft of specific inhibitors of these enzymes that may be used to treat the conditions to which they contribute.