Lymphocyte Survival: A Red Queen Hypothesis

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Science  26 Sep 1997:
Vol. 277, Issue 5334, pp. 1950
DOI: 10.1126/science.277.5334.1950

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A pool of immune cells lies apparently dormant in the body, ready to become activated if awakened by a foreign antigen. In a Perspective Freitas and Rocha discuss the new finding (reported on page 1986 of this issue) that in fact these cells are waiting quite actively, kept in a receptive state by the presence of a transcription factor, LKLF.