The Mechanism of a C-H Bond Activation Reaction in Room-Temperature Alkane Solution

See allHide authors and affiliations

Science  10 Oct 1997:
Vol. 278, Issue 5336, pp. 260-263
DOI: 10.1126/science.278.5336.260

You are currently viewing the abstract.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


Chemical reactions that break alkane carbon-hydrogen (C–H) bonds are normally carried out under conditions of high temperature and pressure because these bonds are extremely strong (∼100 kilocalories per mole), but certain metal complexes can activate C–H bonds in alkane solution under the mild conditions of room temperature and pressure. Time-resolved infrared experiments probing the initial femtosecond dynamics through the nano- and microsecond kinetics to the final stable products have been used to generate a detailed picture of the C–H activation reaction. Structures of all of the intermediates involved in the reaction of Tp*Rh(CO)2 (Tp* = HB–Pz3*, Pz* = 3,5-dimethylpyrazolyl) in alkane solution have been identified and assigned, and energy barriers for each reaction step from solvation to formation of the final alkyl hydride product have been estimated from transient lifetimes.

  • * Present address: Department of Chemistry, Emory University, Atlanta, GA 30322, USA.

  • Present address: Pacific Northwest National Laboratory, Post Office Box 999, Richland, WA 99352, USA.

View Full Text