Neocortical Neurons: Where Do They Come From?

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Science  17 Oct 1997:
Vol. 278, Issue 5337, pp. 402-403
DOI: 10.1126/science.278.5337.402

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As the mature brain forms from an undifferentiated mass of cells, compartments are set up that ultimately become brain regions. Now in this issue, Anderson et al. show that a subpopulation of neural precursor cells travels across one of these boundaries, previously thought to be impenetrable by developing cells. In their Perspective, Lumsden and Gulisano explain what this means for our understanding of how the brain forms.