News and CommentHuman Genetics

Environment Institute Lays Plans for Gene Hunt

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Science  24 Oct 1997:
Vol. 278, Issue 5338, pp. 569-570
DOI: 10.1126/science.278.5338.569

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BETHESDA, MARYLAND-- Toxicologists have found dozens of genes that they think make some individuals more susceptible to pollutants and other environmental chemicals, contributing to everything from cancer to birth defects and Parkinson's disease. Hoping to ferret out dozens more of these "environmental susceptibility" gene variants, National Institutes of Health scientists are putting together a major effort to sequence DNA from perhaps 1000 people to try to demonstrate a link between certain genes and patterns of disease, thereby making it possible to identify and protect people susceptible to environmental hazards.