NewsCancer Research

Treatment Marks Cancer Cells for Death

See allHide authors and affiliations

Science  07 Nov 1997:
Vol. 278, Issue 5340, pp. 1037
DOI: 10.1126/science.278.5340.1037

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


Tumor-suppressor genes are an obvious target for cancer treatment, because they are lost or inactivated in many cancers. Most efforts to exploit these genes have taken a straightforward approach: trying to replace them or mimic their function with some other molecule (see main text). But one candidate cancer treatment tries instead to turn the absence of a tumor suppressor--the p53 gene--into an advantage.