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Heat Shock Protein Linked to Stroke Protection

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Science  21 Nov 1997:
Vol. 278, Issue 5342, pp. 1405
DOI: 10.1126/science.278.5342.1405

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Neuroscientists have identified a molecule that could lead to a new kind of stroke therapy. As reported at the 27th annual meeting of the Society for Neuroscience in New Orleans last month, researchers found that introducing the gene for a heat shock protein--so-called because it is produced in response to increased temperatures or other stresses--into the brains of rats reduced the number of neurons that died after their blood supply was cut off. While the technical obstacles of converting the finding into a therapy for stroke are formidable, researchers say it's not impossible.