Policy Forum

Variations on a Theme: Cataloging Human DNA Sequence Variation

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Science  28 Nov 1997:
Vol. 278, Issue 5343, pp. 1580-1581
DOI: 10.1126/science.278.5343.1580

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New methods for the discovery and scoring of single-nucleotide polymorphisms (SNPs) offer the potential for considerably improved methods for genetic analysis of complex biological phenomena, particularly common diseases. In this Policy Forum, the authors call for a publicly supported effort to discover a large number of SNPs and to place the information in public databases. Participation in this public effort by the private sector would be particularly desirable.