Life in the Balance: Cell Walls and Antibiotic Resistance

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Science  05 Dec 1997:
Vol. 278, Issue 5344, pp. 1731-1732
DOI: 10.1126/science.278.5344.1731b

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In her winning essay for the Pharmacia Biotech & Science Prize for Young Scientists, Jacobs describes her work on the control of cell wall synthesis in bacteria. Her results shed light on how one class of antibiotics (b-lactam antibiotics) kills bacteria and paves the way for the development of new antibacterial drugs.