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NDR1, a Pathogen-Induced Component Required for Arabidopsis Disease Resistance

Science  12 Dec 1997:
Vol. 278, Issue 5345, pp. 1963-1965
DOI: 10.1126/science.278.5345.1963

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Abstract

Plant disease resistance (R) genes confer an ability to resist infection by pathogens expressing specific corresponding avirulence genes. In Arabidopsis thaliana, resistance to both bacterial and fungal pathogens, mediated by several Rgene products, requires the NDR1 gene. Positional cloning was used to isolate NDR1, which encodes a 660–base pair open reading frame. The predicted 219–amino acid sequence suggests that NDR1 may be associated with a membrane. NDR1 expression is induced in response to pathogen challenge and may function to integrate various pathogen recognition signals.

  • * Present address: Biology Department, San Francisco State University, San Francisco, CA 94132, USA.

  • Present address: Department of Plant and Soil Sciences, University of Delaware, Newark, DE 19717, USA.

  • To whom correspondence should be addressed. E-mail: stask{at}nature.berkeley.edu

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