Policy Biomedicine

The Highest Attainable Standard: Ethical Issues in AIDS Vaccines

Science  09 Jan 1998:
Vol. 279, Issue 5348, pp. 186-188
DOI: 10.1126/science.279.5348.186

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Summary

Developing countries have an urgent need for effective and affordable vaccines to prevent AIDS. Trials of HIV vaccines raise complex ethical as well as scientific issues. Some of the existing international guidelines for biomedical research involving human subjects, as applied to clinical trials of HIV vaccines and other interventions, may be in conflict. In addition, the current ethical guidelines fail to address the concern that poor countries may not find it economically or technically possible to implement some recommendations.

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