Research CommentariesDevelopmental Biology

Reprolysins and Astacins ... Alive, Alive-O

Science  16 Jan 1998:
Vol. 279, Issue 5349, pp. 336-337
DOI: 10.1126/science.279.5349.336

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Proteases are common enzymes that cut proteins into pieces. But new work indicates that they do not just perform janitorial duties. The cleavages by proteases are proving to be important regulatory steps, as summarized by Weinmaster in her commentary. She focuses on two instances in which proteases perform essential regulatory jobs during the development of the embryo.