Special Articles

Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal Transduction

See allHide authors and affiliations

Science  23 Jan 1998:
Vol. 279, Issue 5350, pp. 527-533
DOI: 10.1126/science.279.5350.527

You are currently viewing the abstract.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Abstract

In the past few years genetic, biochemical, and cytolocalization data have implicated members of the myosin superfamily of actin-based molecular motors in a variety of cellular functions including membrane trafficking, cell movements, and signal transduction. The importance of myosins is illustrated by the identification of myosin genes as targets for disease-causing mutations. The task at hand is to decipher how the multitude of myosins function at both the molecular and cellular level—a task facilitated by our understanding of myosin structure and function in muscle.

  • * To whom correspondence should be addressed. E-mail: mark.mooseker{at}yale.edu

View Full Text