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10-Gallon Molecule Stomps Tumors

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Science  27 Feb 1998:
Vol. 279, Issue 5355, pp. 1307-1308
DOI: 10.1126/science.279.5355.1307b

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A newly created, larger version of a pigment called porphyrin that ferries iron and other metals in the blood is showing promise as a means of ferrying cancer drugs into tumor cells. In pilot trials, the new molecule, called texaphyrin, has shown promise in enhancing the effects of radiation on inoperable brain tumors, and the National Cancer Institute has now added it to its list of the most promising therapies.