NewsAAAS Meeting

Prodding Cells to Make Proteins

Science  27 Feb 1998:
Vol. 279, Issue 5355, pp. 1308
DOI: 10.1126/science.279.5355.1308b

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New observations, presented at the meeting, of cells hastily setting up protein factories after their internal skeletons are pulled or twisted by forces applied to their surfaces show that mechanical forces on the cell's internal skeleton directly influence protein assembly. The findings, in press at Nature, could lead to a better understanding of how cells grow differently under microgravity and may also aid researchers trying to create better artificial tissues such as blood vessels and, eventually, entire organs.