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Changes in Auxin Response from Mutations in an AUX/IAA Gene

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Science  27 Feb 1998:
Vol. 279, Issue 5355, pp. 1371-1373
DOI: 10.1126/science.279.5355.1371

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Abstract

Transcription of the AUX/IAA family of genes is rapidly induced by the plant hormone auxin, but evidence thatAUX/IAA genes mediate further responses to auxin has been elusive. Changes in diverse auxin responses result from mutations in the Arabidopsis AXR3 gene. AXR3 was shown to be a member of the AUX/IAA family, providing direct evidence thatAUX/IAA genes are central in auxin signaling. Molecular characterization of axr3 gain-of-function and loss-of-function mutations established the functional importance of domains conserved among AUX/IAA proteins.

  • * To whom correspondence should be addressed. E-mail: hmol1{at}york.ac.uk

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