Research NewsPROTEIN DESIGN

The Bare Bones of Catalysis

See allHide authors and affiliations

Science  20 Mar 1998:
Vol. 279, Issue 5358, pp. 1852
DOI: 10.1126/science.279.5358.1852

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

Biochemists using an artificial form of evolution have created a redesigned enzyme that still performs the function of its natural counterpart. By tearing apart an enzyme and pushing its fragments through a round of mutation and selection to recover the original function, researchers report on page 1958 that they have come up with a new, smaller version that is equally adept at the original job.