Research CommentariesTRANSCRIPTION

Promoter Logic

Science  20 Mar 1998:
Vol. 279, Issue 5358, pp. 1871-1872
DOI: 10.1126/science.279.5358.1871

You are currently viewing the summary.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Summary

Promoters, sequences of DNA upstream of the coding region of a gene, confer regulation to the gene, responding to signals to turn up, down, on, or off the gene's transcription. In a research article in this issue, Yuh et al . have so methodically quantitated the function of each module within a sea urchin promoter that they are able to build a computer model of the apparatus. In his commentary, Wray describes the unique features of this well-described promoter and the general principles that it teaches us about the evolution of gene regulation.

Related Content