Research CommentariesImmunology

Update: The Numbers Game for Virus-Specific CD8+ T Cells

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Science  10 Apr 1998:
Vol. 280, Issue 5361, pp. 227
DOI: 10.1126/science.280.5361.227

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Recent advances have, for the first time, allowed accurate quantitation of the virus-specific effector and memory CD8T lymphocyte responses. The T cell numbers are much higher than anyone had previously suspected. The consequence is a revolution in our understanding of cell-mediated immunity in virus infections.