The Key to Success Is Finishing Well

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Science  08 May 1998:
Vol. 280, Issue 5365, pp. 816
DOI: 10.1126/science.280.5365.816

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For genome sequencers, the most challenging part of the job is "finishing"--the final stage in which fragments of raw DNA data are arranged into a completed sequence. Even as robots and computers take over the grunt work, this last step still requires an experienced eye and an innovative mind. Now a new computer program that analyzes machine readouts as a human would is helping sequencing labs to scale up their efforts.