Contents

19 June 1998
Vol 280, Issue 5371

About The Cover

The molecules involved in HIV-1 entry into cells are the envelope glycoproteins gp120 (blue; lacking variable loops) and gp41 (yellow) and cellular receptors CD4 (red) and chemokine receptor (green; hypothetical model). Progress against AIDS requires a clear view of the known, the uncertain, and the deficiencies in research, resources, and societal and governmental commitment. See the special section beginning on 1855 and related items on 1815a, 1844, 1905, and 1949. [Image: R. Wyatt and J. Sodroski; enhanced by K. Sutliff]