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Limitations of a Molecular Clock Applied to Considerations of the Origin of HIV-1

Science  19 Jun 1998:
Vol. 280, Issue 5371, pp. 1868-1871
DOI: 10.1126/science.280.5371.1868

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Abstract

A recent report has provided information that helps to determine the age of a common viral ancestor of the AIDS epidemic. Korber et al. examine the strengths as well as limitations of molecular clock analysis and the implications of the findings for planning vaccines and forecasting the future of the epidemic.

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