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NIH Concocts a Booster Shot for HIV Vaccines

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Science  28 Aug 1998:
Vol. 281, Issue 5381, pp. 1270-1272
DOI: 10.1126/science.281.5381.1270

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When the National Institutes of Health (NIH) decided 4 years ago not to fund large-scale efficacy trials of the leading AIDS vaccines then under development, the move underlined a stark and sobering message: A decade had passed since HIV had been unmasked as the cause of AIDS, yet researchers had not even found a vaccine promising enough to justify the expense of a full-scale test. The field lost what little momentum it had. Now, NIH is trying to give AIDS vaccine research a shot in the arm.