PerspectiveNeuroscience

Driving the Growth Cone

Science  04 Sep 1998:
Vol. 281, Issue 5382, pp. 1465-1466
DOI: 10.1126/science.281.5382.1465

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Summary

Growth cones are the specialized tips of neuronal axons that make their way through the nervous system in search of a correct target. In his Perspective, Caroni outlines the signaling mechanisms that help steer the growth cone as it moves, and discusses a report by Song et al. in this week's issue that completes our understanding of how the cell is attracted or repulsed by various molecules in its environment.