Ribozyme Architectural Diversity Made Visible

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Science  09 Oct 1998:
Vol. 282, Issue 5387, pp. 251-252
DOI: 10.1126/science.282.5387.251

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Ribozymes are RNA molecules that can perform a function usually ascribed to proteins-catalysis. Now, two structures of ribozymes have been published (one in this week's issue of Science and one in this week's Nature) that extend our understanding of how these polymers are put together. Westhof and Michel explain the significance of this advance and how the new structures inform our attempts to model RNA structure over the years.