Microchip Arrays Put DNA on the Spot

Science  16 Oct 1998:
Vol. 282, Issue 5388, pp. 396-399
DOI: 10.1126/science.282.5388.396

You are currently viewing the summary.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


DNA chips, which identify strands of DNA by washing them over an array of samples on a substrate and allowing them to bind onto a sample with complementary sequence, let researchers tune in to the symphony of gene expression. They can, for the first time, see which of the multitude of genes in a cell is active at any one time, an ability that is already speeding the understanding of the functions of genes. And, although only a handful of products exist at the moment, DNA chips also look set to revolutionize drug discovery and diagnostics.