Special Reviews

New Goals for the U.S. Human Genome Project: 1998-2003

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Science  23 Oct 1998:
Vol. 282, Issue 5389, pp. 682-689
DOI: 10.1126/science.282.5389.682

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The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993–98. A new plan, for 1998–2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, 2 years ahead of previous projections. In the course of completing the sequence, a “working draft” of the human sequence will be produced by the end of 2001. The plan also includes goals for sequencing technology development; for studying human genome sequence variation; for developing technology for functional genomics; for completing the sequence ofCaenorhabditis elegans and Drosophila melanogaster and starting the mouse genome; for studying the ethical, legal, and social implications of genome research; for bioinformatics and computational studies; and for training of genome scientists.

  • * To whom correspondence should be addressed: E-mail: fc23a{at}nih.gov

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