Gathering Glycine Receptors at Synapses

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Science  13 Nov 1998:
Vol. 282, Issue 5392, pp. 1277-1279
DOI: 10.1126/science.282.5392.1277

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Neurons send their signals to the next neuron by shooting neurotransmitters across the intracellular gulf to a cluster of receptors on the downstream neuron. As discussed by Froehner in his Perspective, these receptors are held in place by so-called scaffolding proteins on the inside of the cell. A new example of such proteins is reported on page 1321 of this issue. In inhibitory neurons, the glycine receptors are held in place by the protein gephyrin.

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