PerspectiveMolecular Biology

Nuclear Functions Charge Ahead

Science  11 Dec 1998:
Vol. 282, Issue 5396, pp. 2003-2004
DOI: 10.1126/science.282.5396.2003

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A new study in this issue of Science on nuclei of the frog Xenopus (Lund and Dahlberg) shows that, after being transcribed from DNA, transfer RNA molecules must be attached to their amino acid before being exported from the nucleus. This departure from the standard dogma is discussed by Hopper in her Perspective, as is the applicability of this system to other RNAs and other species.