What Maintains Memories?

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Science  15 Jan 1999:
Vol. 283, Issue 5400, pp. 339-340
DOI: 10.1126/science.283.5400.339

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You remember a favorite toy from childhood. Something must be stably altered in your brain to encode this memory. But what? Lisman and Fallon outline the possible candidates at present, including a biochemical feedback loop presented by Bhalla and Iyengar in this issue.