SITE VISIT: DNA Vaccine Boosterism

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Science  22 Jan 1999:
Vol. 283, Issue 5401, pp. 455
DOI: 10.1126/science.283.5401.455a

Vaccines made with DNA have burst onto the research scene in the past 5 years, and a handful of formulations, including one against Lyme disease, have reached the market. For the latest information on vaccines in development against diseases such as rabies, malaria, and herpes, check out the DNA Vaccine Web.

DNA shots are a hot commodity, as some may prove cheaper and easier to manufacture than traditional protein-based vaccines, according to the DNA Vaccine Web. For newcomers to this area, the site briefly describes how the vaccines work (viral or bacterial DNA is injected into a patient, whose genetic machinery uses it as a template to make a protein against which the person's immune system can generate antibodies). The site links to news stories on DNA vaccines, and every month creator Robert Whalen, a vaccinologist at the Centre National de la Recherche Scientifique in Paris, updates a list of 1900 papers and counting on the subject. Whalen also chronicles upcoming meetings, lab protocols, and vaccine missives from the U.S. Food and Drug Administration.

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