NewsSINGLE MOLECULES

Deconstructing DNA for Faster Sequencing

See allHide authors and affiliations

Science  12 Mar 1999:
Vol. 283, Issue 5408, pp. 1669
DOI: 10.1126/science.283.5408.1669

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

At the heart of the international race to sequence the human genome are machines that create thousands of copies of DNA fragments as a first step toward decoding their sequence, one nucleotide base pair at a time. But a handful of groups around the world are working on new approaches that decode single copies of DNA directly using molecular probes--approaches which have the potential to simplify and speed up the sequencing process.