Building Working Cells 'in Silico'

Science  02 Apr 1999:
Vol. 284, Issue 5411, pp. 80-81
DOI: 10.1126/science.284.5411.80b

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A computer scientist and biologist has come up with a scheme for exploring the effects that only emerge when a cell's many processes interact: a simulation program called E-CELL that can reproduce, in simplified form, a cell's biochemical symphony. Other computer models of the cell are being developed that reproduce individual cellular processes in detail; E-CELL, in contrast, is designed to paint a broad-brush picture of the cell as a whole.