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Morphological Clues from Multilegged Frogs: Are Retinoids to Blame?

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Science  30 Apr 1999:
Vol. 284, Issue 5415, pp. 800-802
DOI: 10.1126/science.284.5415.800

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Abstract

Morphological analysis was performed on multilegged deformed frogs representing five species from 12 different localities in California, Oregon, Arizona, and New York. The pattern of duplicated limbs was consistent with mechanical perturbation by trematode infestation but not with the effects of retinoids.

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