News FocusChemistry

Drug Industry Looks to the Lab Instead of Rainforest and Reef

See allHide authors and affiliations

Science  09 Jul 1999:
Vol. 285, Issue 5425, pp. 186
DOI: 10.1126/science.285.5425.186

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

LA JOLLA, CALIFORNIA-- Chemists who synthesize complex organic molecules from scratch take their lessons from nature, trying to mimic the complex, pharmacologically active molecules made by obscure living things. The field is at a turning point, with some chemists arguing that it isn't producing the fundamental insights of the past (see main text). And, to add to its troubles, natural products discovery--the effort to find candidate drugs in natural sources, which provides the chemists with their targets--has run into troubles of its own.