The Constant Junction

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Science  15 Oct 1999:
Vol. 286, Issue 5439, pp. 424-425
DOI: 10.1126/science.286.5439.424

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How the neuromuscular junction (where a nerve cell meets muscle) maintains its high density of acetylcholine receptors in the postsynaptic muscle membrane has been a matter of conjecture. In her Perspective, Miriam Salpeter discusses new findings showing that nerve activity regulates the stability of acetylcholine receptors ( Akaaboune et al.).