Gels and Genomes

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Science  15 Oct 1999:
Vol. 286, Issue 5439, pp. 429
DOI: 10.1126/science.286.5439.429

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The requirement for inexpensive, very accurate high throughput sequencing is even more crucial now that information from the human genome sequencing project is starting to emerge. In particular several projects are underway to sequence selected regions of the genomes of many different individuals in an effort to pinpoint single nucleotide polymorphisms that are associated with human disease. In a TechView article, Jane Rogers of the Sanger Centre discusses the latest developments in sequencing technology, many of which were presented at the recent International Conference on Automation in Mapping and DNA Sequencing.