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Neurogenesis in the Neocortex of Adult Primates

Science  15 Oct 1999:
Vol. 286, Issue 5439, pp. 548-552
DOI: 10.1126/science.286.5439.548

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Abstract

In primates, prefrontal, inferior temporal, and posterior parietal cortex are important for cognitive function. It is shown that in adult macaques, new neurons are added to these three neocortical association areas, but not to a primary sensory area (striate cortex). The new neurons appeared to originate in the subventricular zone and to migrate through the white matter to the neocortex, where they extended axons. These new neurons, which are continually added in adulthood, may play a role in the functions of association neocortex.

  • * To whom correspondence should be addressed. E-mail: goulde{at}princeton.edu

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