Culling Genes Early Yields Rich Harvest

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Science  03 Mar 2000:
Vol. 287, Issue 5458, pp. 1572-1573
DOI: 10.1126/science.287.5458.1572

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CHANTILLY, VIRGINIA-- A team of human sequencers using high-powered computers has just finished assembling the entire genetic sequence of the common bacterium Caulobacter crescentus. The feat, announced at a meeting on microbial genomes held here last month, marked another important milestone in the burgeoning business of gene sequencing. But the real news was that even before the sequence was completed, another team had scoured the emerging data and found several hundred new genes involved in the bacterium's cell cycle.