A Furtive Pathogen Revealed

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Science  10 Mar 2000:
Vol. 287, Issue 5459, pp. 1767-1768
DOI: 10.1126/science.287.5459.1767

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The pathogenic bacterium Neisseria meningitidis is the cause of meningococcal meningitis. Although a vaccine is available for Neisseria of serogroups A and C, there is no vaccine available for serogroup B. In a Perspective, Nassif reports on the sequencing of the complete genome of N. meningitidis type B strain MC58 ( Tettelin et al.) and the mining of this genome to identify highly conserved surface proteins that may be valuable as vaccine antigens ( Pizza et al.).