Receptors as Kissing Cousins

See allHide authors and affiliations

Science  07 Apr 2000:
Vol. 288, Issue 5463, pp. 65-67
DOI: 10.1126/science.288.5463.65

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


It has always been assumed that the numerous members of the huge GPCR family of receptors function in isolation. However, as Graeme Milligan discusses in a Perspective, a host of new findings ( Rocheville et al.) now suggest that related but different GPCRs can bind to each other, and when they do their properties are altered.