News FocusGenetics

Zebrafish Earns Its Stripes in Genetic Screens

See allHide authors and affiliations

Science  19 May 2000:
Vol. 288, Issue 5469, pp. 1160-1161
DOI: 10.1126/science.288.5469.1160

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


COLD SPRING HARBOR, NEW YORK-- Because it is a vertebrate, the zebrafish is genetically closer to humans than flies or worms, and its small size, quick generation time, and inexpensive care make it possible to keep thousands of fish in a single lab. Add to that the transparency of its young, and you have what some consider an ideal lab animal. As was demonstrated at a recent meeting here, researchers are using various clever techniques to identify zebrafish mutants with which to probe the genes involved in a wide variety of human maladies, from obesity to bone diseases.