Australian 'Ranch' Gears Up to Mass-Produce Mutant Mice

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Science  02 Jun 2000:
Vol. 288, Issue 5471, pp. 1572-1573
DOI: 10.1126/science.288.5471.1572

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CANBERRA, AUSTRALIA-- Chris Goodnow, an immunologist here at the Australian National University, is using the latest technology and sequencing data to advance research on recessive mutations that cause adult-onset diseases. The plan is to generate mouse mutants on a massive scale in order to help assign functions to the genes being identified by the Human Genome Project. Because mouse genes are thought to do the same thing as their human counterparts, scientists hope to translate the knowledge into clinical studies.