Report

Generalized Potential of Adult Neural Stem Cells

Science  02 Jun 2000:
Vol. 288, Issue 5471, pp. 1660-1663
DOI: 10.1126/science.288.5471.1660

You are currently viewing the abstract.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Abstract

The differentiation potential of stem cells in tissues of the adult has been thought to be limited to cell lineages present in the organ from which they were derived, but there is evidence that some stem cells may have a broader differentiation repertoire. We show here that neural stem cells from the adult mouse brain can contribute to the formation of chimeric chick and mouse embryos and give rise to cells of all germ layers. This demonstrates that an adult neural stem cell has a very broad developmental capacity and may potentially be used to generate a variety of cell types for transplantation in different diseases.

  • * To whom correspondence should be addressed. E-mail jonas.frisen{at}cmb.ki.se

View Full Text

Cited By...