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Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations

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Science  30 Jun 2000:
Vol. 288, Issue 5475, pp. 2354-2357
DOI: 10.1126/science.288.5475.2354

Article Information

vol. 288 no. 5475 2354-2357

PubMed: 
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History: 
  • Received for publication December 28, 1999
  • Accepted for publication April 21, 2000

Author Information

  1. Richard M. Siegel1,
  2. John K. Frederiksen1,
  3. David A. Zacharias2,
  4. Francis Ka-Ming Chan1,
  5. Michele Johnson1,
  6. David Lynch3,
  7. Roger Y. Tsien2,
  8. Michael J. Lenardo1,*
  1. 1 Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  2. 2 Howard Hughes Medical Institute and Department of Pharmacology, University of California, San Diego School of Medicine, La Jolla, CA 92093, USA.
  3. 3 Immunex Corporation, 51 University Street, Seattle, WA 98101, USA.

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