PerspectiveCell Biology

Travel Bulletin--Traffic Jams Cause Tumors

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Science  07 Jul 2000:
Vol. 289, Issue 5476, pp. 67-69
DOI: 10.1126/science.289.5476.67

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All animal cells have a polarity, that is, different proteins are clustered in distinct domains of the plasma membrane and these regions carry out different jobs. As Peifer discusses in a lively Perspective, new work ( Bilder et al.) identifies some of the molecular characters that direct proteins to their different cellular destinations.