PerspectiveMolecular Biology

Transposase Team Puts a Headlock on DNA

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Science  07 Jul 2000:
Vol. 289, Issue 5476, pp. 73-74
DOI: 10.1126/science.289.5476.73

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Summary

Transposable DNA elements jump from one location in the genome to another. But, the cut-and-paste molecular machinations that support this nomadic lifestyle are still being unraveled. In their Perspective, Williams and Baker at the Massachusetts Institute of Technology discuss new details of transposon relocation revealed through resolution of the structure of a transposase enzyme bound to DNA ( Davies et al.).