PerspectiveDevelopment

p73--Guilt by Association?

Science  14 Jul 2000:
Vol. 289, Issue 5477, pp. 257-258
DOI: 10.1126/science.289.5477.257

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Summary

It has been assumed that the new members of the p53 protein family, p63 and p73, would have the same job as p53, namely, forcing cells to die if they or their DNA is damaged. Now, as Morrison and Kinoshita explain in their Perspective, one particular form of p73 has been found to be a survival factor rather than a death factor for sympathetic neurons during development ( Pozniak et al.).

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